A Case Report of Small Cell Lung Carcinoma in a Patient with Progressive Diffuse Sclerosis

Abstract

Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is rare. This reports presents a 54-year-old non-smoker woman with a history of scleroderma who was examined due to aggravation of shortness of breath and cough for the last two months. On radiography and CT scan, a mass was seen in the sub pleural area of the upper right lobe of the right lung, and pathological examination showed small cell carcinoma of the lung. Small cell carcinoma is very rare in non-smokers, therefore, it may be associated with interstitial lung tissue disease in scleroderma.

Keywords

• scleroderma
• small cell lung cancer
• dyspnea