Differentiation syndrome in patients with acute promyelocytic leukemia

Nusiba H. Elamin; Farah Rashid; Muhammad S. Afana; Honar Cherif; Mohamed A. Yassin

doi:10.1002/ccr3.6697

Clinical Case Reports (Jan 2023)

Differentiation syndrome in patients with acute promyelocytic leukemia

Nusiba H. Elamin,
Farah Rashid,
Muhammad S. Afana,
Honar Cherif,
Mohamed A. Yassin

Affiliations

Nusiba H. Elamin: Department of Internal Medicine Hamad General Hospital, Hamad Medical Corporation Doha Qatar
Farah Rashid: Department of Internal Medicine Hamad General Hospital, Hamad Medical Corporation Doha Qatar
Muhammad S. Afana: Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research Hamad Medical Corporation Doha Qatar
Honar Cherif: Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research Hamad Medical Corporation Doha Qatar
Mohamed A. Yassin: Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research Hamad Medical Corporation Doha Qatar

DOI: https://doi.org/10.1002/ccr3.6697
Journal volume & issue: Vol. 11, no. 1
pp. n/a – n/a

Abstract

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Abstract A 48‐year‐old male diagnosed with acute promyelocytic leukemia (APL) started on all‐trans‐retinoic acid and arsenic trioxide, developed typical symptoms of differentiation syndrome, and improved dramatically on steroids. Hence, any APL patient started on chemotherapy, needs to be monitored closely for developing differentiation syndrome and to start steroid upon suspicion.

Published in Clinical Case Reports

ISSN: 2050-0904 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General)
Website: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2050-0904

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Abstract

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