Isolation of Polyphenols from Soursop (Annona muricata L.) Leaves Using Green Chemistry Techniques and their Anticancer Effect

Abstract

HIGHLIGHTS Isolate, fractionate and characterize extracts obtained from soursop leaves. Use of emerging green technologies such as microwave-ultrasound hybridization. The extracts contain kaempferol, procyanidins, catechin, and quercetin. The total ethanolic extract demonstrates cytotoxic effect on HeLa cells.

Keywords

• green solvents
• microwave-ultrasound
• soursop
• polyphenols
• HeLa