PLoS ONE (Jan 2024)

Prevalence of fatigue and cognitive impairment after traumatic brain injury.

  • Traver J Wright,
  • Timothy R Elliott,
  • Kathleen M Randolph,
  • Richard B Pyles,
  • Brent E Masel,
  • Randall J Urban,
  • Melinda Sheffield-Moore

DOI
https://doi.org/10.1371/journal.pone.0300910
Journal volume & issue
Vol. 19, no. 3
p. e0300910

Abstract

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BackgroundFollowing traumatic brain injury (TBI) some patients develop lingering comorbid symptoms of fatigue and cognitive impairment. The mild cognitive impairment self-reported by patients is often not detected with neurocognitive tests making it difficult to determine how common and severe these symptoms are in individuals with a history of TBI. This study was conducted to determine the relative prevalence of fatigue and cognitive impairment in individuals with a history of TBI.MethodsThe Fatigue and Altered Cognition Scale (FACs) digital questionnaire was used to assess self-reported fatigue and cognitive impairment. Adults aged 18-70 were digitally recruited for the online anonymous study. Eligible participants provided online consent, demographic data, information about lifetime TBI history, and completed the 20 item FACs questionnaire.ResultsA total of 519 qualifying participants completed the online digital study which included 204 participants with a history of TBI of varied cause and severity and 315 with no history of TBI. FACs Total Score was significantly higher in the TBI group (57.7 ± 22.2) compared to non-TBI (39.5 ± 23.9; pConclusionsAdults with a history of even mild TBI report significantly greater fatigue and cognitive impairment than those with no history of TBI, and symptoms are more profound with greater TBI severity.