Nature Communications (Oct 2018)

Dereplication of microbial metabolites through database search of mass spectra

  • Hosein Mohimani,
  • Alexey Gurevich,
  • Alexander Shlemov,
  • Alla Mikheenko,
  • Anton Korobeynikov,
  • Liu Cao,
  • Egor Shcherbin,
  • Louis-Felix Nothias,
  • Pieter C. Dorrestein,
  • Pavel A. Pevzner

DOI
https://doi.org/10.1038/s41467-018-06082-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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New natural products can be identified via mass spectrometry by excluding all known ones from the analysis, a process called dereplication. Here, the authors extend a previously published dereplication algorithm to different classes of secondary metabolites.