Nature Communications (Dec 2016)
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
Abstract
There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.