BMC Research Notes (Sep 2020)

Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)

  • Troels Thim,
  • Matthias Götberg,
  • Ole Fröbert,
  • Robin Nijveldt,
  • Niels van Royen,
  • Sergio Bravo Baptista,
  • Sasha Koul,
  • Thomas Kellerth,
  • Hans Erik Bøtker,
  • Christian Juhl Terkelsen,
  • Evald Høj Christiansen,
  • Lars Jakobsen,
  • Steen Dalby Kristensen,
  • Michael Maeng

DOI
https://doi.org/10.1186/s13104-020-05252-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 3

Abstract

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Abstract Objective To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). Results We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5–32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.

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