Cutaneous Plasmablastic Lymphoma in an Immunocompetent Patient with Long-Term Pyrimethamine Use for Essential Thrombocythemia: A Case Report and Literature Review

Ing Soo Tiong; Magreet Strauss; Michael B. Y. Lau; Shingirai Chiruka

doi:10.1155/2013/541783

Case Reports in Hematology (Jan 2013)

Cutaneous Plasmablastic Lymphoma in an Immunocompetent Patient with Long-Term Pyrimethamine Use for Essential Thrombocythemia: A Case Report and Literature Review

Ing Soo Tiong,
Magreet Strauss,
Michael B. Y. Lau,
Shingirai Chiruka

Affiliations

Ing Soo Tiong: Southern Blood and Cancer Service, Dunedin Hospital, Private Bag 1921, Dunedin 9054, New Zealand
Magreet Strauss: Division of Haematology, Southern Community Laboratories, Dunedin 9016, New Zealand
Michael B. Y. Lau: Division of Haematology, Southern Community Laboratories, Dunedin 9016, New Zealand
Shingirai Chiruka: Southern Blood and Cancer Service, Dunedin Hospital, Private Bag 1921, Dunedin 9054, New Zealand

DOI: https://doi.org/10.1155/2013/541783
Journal volume & issue: Vol. 2013

Abstract

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We report a case of Epstein-Barr-virus-(EBV-) positive primary cutaneous plasmablastic lymphoma in a human-immunodeficiency-virus-(HIV-) negative, immunocompetent 62-year-old female patient. We postulate that her lymphoma development is due to the longstanding use of pyrimethamine for essential thrombocythemia. This has never been described in the literature.

Published in Case Reports in Hematology

ISSN: 2090-6560 (Print); 2090-6579 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: https://onlinelibrary.wiley.com/journal/3191

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