Mycology (Jun 2024)

New bioactive secondary metabolites from fungi: 2023

  • Ying Shi,
  • Minhui Ji,
  • Jiayu Dong,
  • Dongxiao Shi,
  • Yitong Wang,
  • Longhui Liu,
  • Shuangshuang Feng,
  • Ling Liu

DOI
https://doi.org/10.1080/21501203.2024.2354302

Abstract

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Fungi have been identified as a prolific source of structurally unique secondary metabolites, many of which display promising biological and pharmacological properties. This review provides an overview of the structures of new natural products derived from fungi and their biological activities along with the research strategies, which focuses on literature published in the representative journals in 2023. In this review, a total of 553 natural products including 219 polyketides, 145 terpenoids, 35 steroids, 106 alkaloids, and 48 peptides are presented. By summarising the latest findings, this review aims to provide a guide and inspire further innovation in the fields of the discovery of fungal natural products and pharmaceutical development.

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