mSphere
(Apr 2021)
An Assessment of Siderophore Production, Mucoviscosity, and Mouse Infection Models for Defining the Virulence Spectrum of Hypervirulent Klebsiella pneumoniae
Thomas A. Russo,
Ulrike MacDonald,
Sidra Hassan,
Ellie Camanzo,
Francois LeBreton,
Brendan Corey,
Patrick McGann
Affiliations
Thomas A. Russo
ORCiD Veterans Administration Western New York Healthcare System, Buffalo, New York, USA
Ulrike MacDonald
Veterans Administration Western New York Healthcare System, Buffalo, New York, USA
Sidra Hassan
Veterans Administration Western New York Healthcare System, Buffalo, New York, USA
Ellie Camanzo
Department of Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
Francois LeBreton
Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
Brendan Corey
Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
Patrick McGann
ORCiD Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
DOI
https://doi.org/10.1128/mSphere.00045-21
Journal volume & issue
Vol. 6,
no. 2
Abstract
Read online
The pathogenic potential of hvKp strains is primarily mediated by a large virulence plasmid. The minimal set of genes required for the full expression of the hypervirulent phenotype is undefined.
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