The frequency, associated risk factors, surgical management and long term outcomes of olfactory groove meningioma

Abstract

Aim: Olfactory groove meningiomas (OGMs) are rare, benign tumours representing a third of all intracranial tumours. This study examined the frequency, associated risk factors, surgical management, complications, recurrence rate and mortality of patients diagnosed with OGMs. Methods: A retrospective study of patients admitted with OGMs to the neurosurgical department of Spitalul Judeţean in Oradea, Romania between 2005 and 2006. History, physical examination, imaging, surgical approach, World Health Organization (WHO) histological grading, Simpsons grading for tumour removal and functional assessments were reviewed and appropriate statistical tests performed. Result: A total of 22 patients were admitted with OGMs to the neurosurgical department of Spitalul Judeţean in Oradea, between 2005 and 2006. The mean age of presentation was 61 ± 13 years, 73% were females and the commonest presenting symptoms were anosmia, visual impairment, headache, and memory loss. The median tumour size at diagnosis was 5.58 cm (IQR 2.81–8.9) of which 41% were > 6 cm. In all cases, most patients (59%) had pterional approach, total tumour removal (Simpson grade I or II) was achieved in 95% of patients. The most common postoperative complications were cerebral oedema, haemorrhage and local wound infection. There were no immediate postoperative mortality and there were no tumour recurrence following a median follow up of 72 months. There was significant improvement in the performance status of patients at follow up with p = 0.001. Conclusion: In this cohort, total tumour removal was achieved in 95% of patients, mostly performed via pterional approach with no tumour recurrence at follow up.

Keywords

• Olfactory groove meningioma
• Bifrontal approach
• Pterional approach
• Tumour recurrence
• Performance status
• Benign intracranial tumour