Nature Communications (Oct 2019)

Split selectable markers

  • Nathaniel Jillette,
  • Menghan Du,
  • Jacqueline Jufen Zhu,
  • Peter Cardoz,
  • Albert Wu Cheng

DOI
https://doi.org/10.1038/s41467-019-12891-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 8

Abstract

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Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.