THE DEGREE OF INHIBITION OF BARIUM SULPHATE INDUCED LUMINOL-DEPENDENT CHEMILUMINESCENCE OF BLOOD UNDER THE INFLUENCE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, TARTRAZINE DEPENDING ON THE LIMITATIONS OF INTOLERANCE TO THESE AGENTS

Abstract

We investigated the intensity of barium sulfate stimulated luminol-dependent chemiluminescence (SLCHL) blood after pre-incubation of blood samples with nonsteroidal anti-inflammatory drugs (NSAIDs), food dye tartrazine in healthy donors and patients with intolerance to NSAIDS, tarirezine with different clinical manifestations. In patients with bronchial manifestations of intolerance to NSAIDS, tarirezine degree of suppression of SLCHL blood increases with the age of the intolerance. Only patients with skin manifestations of intolerance to NSAIDS (urticaria/angioedema) the degree of suppression of SLCHL blood degrades with the age of the intolerance of these agents.

Keywords

• непереносимость нестероидных противовоспалительных препаратов
• непереносимость тартразина
• хемилюминесценция
• non-steroidal anti-inflammatory drugs intolerance
• tartrazine intolerance
• chemiluminescence