Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial

• Nick A Francis,
• Kerenza Hood,
• Mark Lown,
• Chris C Butler,
• Rachel Lowe,
• James Downs,
• Victoria Shepherd,
• Mina Davoudianfar,
• Jane Davies,
• Alun Toghill,
• Eleri Owen-Jones,
• Katy Addison,
• Tony Bayer,
• Alison Edwards,
• Richard Fuller,
• Helen Stanton,
• Mandy Wootton

Affiliations

Nick A Francis

Primary Care Research Centre, School of Primary Care Population Sciences and Medical Education, University of Southampton, Southampton, UK

Kerenza Hood

Centre for Trials Research, Cardiff University, Cardiff, South Glamorgan, UK

Mark Lown

clinical lecturer

Chris C Butler

2 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

Rachel Lowe

Centre for Trials Research, Cardiff University, Cardiff, UK

James Downs

7 Lay Representative, Cardiff, UK

Victoria Shepherd

Centre for Trials Research, Cardiff University, Cardiff, UK

Mina Davoudianfar

2Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

Jane Davies

2Imperial College London

Alun Toghill

3PPI/Service user representative

Eleri Owen-Jones

1 Centre for Trials Research, Cardiff University, Cardiff, UK

Katy Addison

1 Centre for Trials Research, Cardiff University, Cardiff, UK

Tony Bayer

3 Division of Population Medicine, School of Medicine, Neuadd Meirionnydd, Cardiff University, Cardiff, UK

Alison Edwards

1 Centre for Trials Research, Cardiff University, Cardiff, UK

Richard Fuller

2 Primary Care and Population Sciences, University of Southampton, Aldermoor Health Centre, Southampton, UK

Helen Stanton

1 Centre for Trials Research, Cardiff University, Cardiff, UK

Mandy Wootton

8 Specialist Antimicrobial Chemotherapy Unit, Public Health Wales Microbiology Cardiff, University Hospital of Wales, Cardiff, UK