Spectrophotometric Determination of Epinephrine in Pharmaceutical Preparations Using Praseodymium as Mediating Metals

Baghdad Science Journal. 2011;8(1) DOI 10.21123/bsj.8.1.110-117

 

Journal Homepage

Journal Title: Baghdad Science Journal

ISSN: 2078-8665 (Print); 2411-7986 (Online)

Publisher: College of Science for Women, University of Baghdad

LCC Subject Category: Science

Country of publisher: Iraq

Language of fulltext: Arabic, English

Full-text formats available: PDF

 

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Baghdad Science Journal

EDITORIAL INFORMATION

Blind peer review

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Instructions for authors

Time From Submission to Publication: 24 weeks

 

Abstract | Full Text

A simple, accurate and sensitive spectrophotometric method for the determinaion of epinephrine is described . The method is based on the coordination of Pr (III) with epinephrine at pH 6. Absorbance of the resulting orange yellow complex is measured at 482 nm . A graph of absorbance versus concentrations shows that beer 's low is obeyed over the concentration range (1-50)mg.ml-1 of epinephrine with molar absorpitivity of ( 2.180x103 L.mol-1.cm-1 ), a sandell sensitivity of (0.084 mg.cm-2 ), a relative error of (-2.83%) , a corrolation coffecient (r= 0.9989) and recovery % ( 97.03 ± 0.75 ) depending on the concentration.This method is applied to analyse EP in several commercially available pharmaceutical preparations using direct methods .All statistical calculations are implemented via a Minitab software version 11.