Nature Communications (Jul 2020)

Exploiting natural chemical photosensitivity of anhydrotetracycline and tetracycline for dynamic and setpoint chemo-optogenetic control

  • Armin Baumschlager,
  • Marc Rullan,
  • Mustafa Khammash

DOI
https://doi.org/10.1038/s41467-020-17677-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Anhydrotetracycline and tetracycline are commonly used chemicals to regulate transcription and translation, respectively. Here the authors exploit the natural photosensitivity of these molecules to place their activity under optical control.