Communications Biology (Dec 2020)

Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection

  • Eun Young Yu,
  • Syed S. Zahid,
  • Swapna Ganduri,
  • Jeanette H. Sutherland,
  • Min Hsu,
  • William K. Holloman,
  • Neal F. Lue

DOI
https://doi.org/10.1038/s42003-020-01505-z
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 12

Abstract

Read online

Yu et al. provide evidence that Ustilago maydis employs two structurally distinct telomere-binding proteins to perform complementary functions in telomere maintenance in this organism. While UmTay1 regulates primarily telomere replication and recombination, UmTrf2 is responsible for telomere protection.