Thyroid autoantibodies in hemoblastoses and cytopenias

Abstract

Aim. To study the level of thyroid antibodies (TAB) in blood diseases. Material and methods. TAB levels dynamics was studied in 413 patients with hematological diseases. Results. Increased incidence of cases with high Ab titer to thyroid microsomal antigen was found. High and moderate tilers were revealed in 33% of all examinees, including 41%, 22%, 32% and 29% among patients with immune cytopenia, chronic lymphoid leukemia, generalized mature-cell lymphoma and myeloproliferative diseases, respectively. These high and moderate titers were rather stable. In 15% patients Ab were elevated insignificantly, this rise being unstable. Conclusion. Stable high titers of antibodies to thyroid antigens point to increased incidence rates of concomitant autoimmune hyroiditis in patients with blood diseases.

Keywords

• autoimmune thyroiditis
• antibodies
• microsomal antigen to the thyroid
• thyroglobulin
• autoimmune hemolytic anemia
• idiopathic thrombocytopenic purpura
• cytopenia