Nature Communications (Jul 2022)
Population genomics of ancient and modern Trichuris trichiura
- Stephen R. Doyle,
- Martin Jensen Søe,
- Peter Nejsum,
- Martha Betson,
- Philip J. Cooper,
- Lifei Peng,
- Xing-Quan Zhu,
- Ana Sanchez,
- Gabriela Matamoros,
- Gustavo Adolfo Fontecha Sandoval,
- Cristina Cutillas,
- Louis-Albert Tchuem Tchuenté,
- Zeleke Mekonnen,
- Shaali M. Ame,
- Harriet Namwanje,
- Bruno Levecke,
- Matthew Berriman,
- Brian Lund Fredensborg,
- Christian Moliin Outzen Kapel
Affiliations
- Stephen R. Doyle
- Wellcome Sanger Institute
- Martin Jensen Søe
- Department of Plant and Environmental Sciences, University of Copenhagen
- Peter Nejsum
- Department of Clinical Medicine, Aarhus University
- Martha Betson
- School of Veterinary Medicine, University of Surrey
- Philip J. Cooper
- Institute of Infection and Immunity, St George’s University of London
- Lifei Peng
- Department of Parasitology, School of Basic Medical Sciences, Guangdong Medical University
- Xing-Quan Zhu
- College of Veterinary Medicine, Shanxi Agricultural University
- Ana Sanchez
- Department of Health Sciences, Brock University, St. Catharines
- Gabriela Matamoros
- Microbiology Research Institute, Ciudad Universitaria, Universidad Nacional Autónoma de Honduras
- Gustavo Adolfo Fontecha Sandoval
- Microbiology Research Institute, Ciudad Universitaria, Universidad Nacional Autónoma de Honduras
- Cristina Cutillas
- Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Sevilla
- Louis-Albert Tchuem Tchuenté
- Faculty of Sciences, University of Yaoundé I
- Zeleke Mekonnen
- Institute of Health, School of Medical Laboratory Sciences, Jimma University
- Shaali M. Ame
- Public Health Laboratory Ivo de Carneri
- Harriet Namwanje
- Vector Control Division, Ministry of Health
- Bruno Levecke
- Department of Translational Physiology, Infectiology and Public Health, Ghent University
- Matthew Berriman
- Wellcome Sanger Institute
- Brian Lund Fredensborg
- Department of Plant and Environmental Sciences, University of Copenhagen
- Christian Moliin Outzen Kapel
- Department of Plant and Environmental Sciences, University of Copenhagen
- DOI
- https://doi.org/10.1038/s41467-022-31487-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
The whipworm Trichuris trichiura is a soil-transmitted helminth that causes the neglected tropical disease trichuriasis in humans. Here, the authors produce whole genome sequences of modern and ancient samples from humans and non-human primates to characterise the genomic diversity and evolution of this pathogen.
