Jichu yixue yu linchuang (Mar 2023)

Research progress on the role of DNA methylation in the occurrence and prognosis of lung cancer

  • XUE Jianchao, WANG Yadong, LI Bowen, LIU Xinyu, LIANG Naixin, LI Shanqing

DOI
https://doi.org/10.16352/j.issn.1001-6325.2023.03.514
Journal volume & issue
Vol. 43, no. 3
pp. 514 – 518

Abstract

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Lung cancer is a leading cause of cancer-related morbidity and mortality in China. Early recurrence is the main cause of poor prognosis. The existing prognostic indicators are insufficient. Thus, it is urgent to find reliable prognostic indicators. DNA methylation is the most important epigenetic change in the development of lung cancer. With the development of high-throughput sequencing technology, DNA methylation has shown its great clinical value in the prognosis prediction of lung cancer patients due to its stable and detectable features.

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