SynOpen (Apr 2018)

Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

  • Rakhee Choudhary,
  • Rekha Bai,
  • Pratibha Singh,
  • Mahesh C. Sharma,
  • Satpal Singh Badsara

DOI
https://doi.org/10.1055/s-0037-1610167
Journal volume & issue
Vol. 02, no. 02
pp. 0213 – 0221

Abstract

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Abstract A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of phosphine oxides under the reaction conditions employed, providing the desired products in up to quantitative yields.

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