Biological Therapy of Crohn’s Disease in Ukraine

Abstract

The article assesses the state of the problem of Crohn’s disease (CD) in Ukraine and the world. There has been carried out a comparative analysis of the effectiveness of using standard, as well as biological therapy in the treatment of CD by the data of prospective randomized trials. Own data on the effectiveness of biological therapy in 47 patients with inflammatory bowel disease are provided, as well as a clinical case of the use of tumor necrosis factor α antagonists. The use of drugs of biological therapy is highly effective in patients with CD in inefficiency of standard therapy, may prolong the periods of stable clinical and endoscopic remission, delay the onset of complications and the need for surgical interventions that will improve the quality of life of patients with CD.