Yixue xinzhi zazhi (Feb 2023)

Application of organoid models in colorectal cancer research

  • Zhi-Li LI,
  • Lu WANG,
  • Yu-Ting WANG,
  • Chu-Yue HUANG,
  • An-Qi WANG,
  • Zheng-Rong LYU,
  • Zhi-Min FAN

DOI
https://doi.org/10.12173/j.issn.1004-5511.202208031
Journal volume & issue
Vol. 33, no. 1
pp. 62 – 67

Abstract

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Organoid is a new research tool that has gradually emerged in recent years. They promise to have a broad application prospect in the fields of disease development, drug screening, new drug development, per-sonalized medicine and other fields. Nowadays, the colorectal cancer organoid model has become relatively mature. This paper reviews the common models in colorectal cancer research and the construction and applica-tion of colorectal cancer organoids.

Keywords