Critical Care Explorations (Dec 2023)

Unifying Fluid Responsiveness and Tolerance With Physiology: A Dynamic Interpretation of the Diamond–Forrester Classification

  • Jon-Émile S. Kenny, MD, MSc,
  • Ross Prager, MD,
  • Philippe Rola, MD,
  • Korbin Haycock, MD,
  • John Basmaji, MD,
  • Glenn Hernández, MD, PhD

DOI
https://doi.org/10.1097/CCE.0000000000001022
Journal volume & issue
Vol. 5, no. 12
p. e1022

Abstract

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Point of care ultrasound (POCUS) is a first-line tool to assess hemodynamically unstable patients, however, there is confusion surrounding intertwined concepts such as: “flow,” “congestion,” “fluid responsiveness (FR),” and “fluid tolerance.” We argue that the Frank–Starling relationship is clarifying because it describes the interplay between “congestion” and “flow” on the x-axis and y-axis, respectively. Nevertheless, a single, simultaneous assessment of congestion and flow via POCUS remains a static approach. To expand this, we propose a two-step process. The first step is to place the patient on an ultrasonographic Diamond–Forrester plot. The second step is a dynamic assessment for FR (e.g., passive leg raise), which individualizes therapy across the arc of critical illness.