Molecules (Nov 2002)

A Synthesis of 6-(2,5-Dimethoxy-4-(2-aminopropyl)phenyl)-hexylthiol. A Ligand for Conjugation with Fluorescent Cadmium Selenide/Zinc Sulfide Core/Shell Nanocrystals and Biological Imaging

  • Sandra J. Rosenthal,
  • Jesse L. Grey,
  • Ian D. Tomlinson

DOI
https://doi.org/10.3390/71100777
Journal volume & issue
Vol. 7, no. 11
pp. 777 – 790

Abstract

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The synthesis of 6-(2,5-dimethoxy-4-(2-aminopropyl)phenyl)hexylthiol, an agonist with a very high affinity for the 5HT2A serotonin receptor subtype is reported. This agonist was designed to be attached to highly fluorescent cadmium selenide/zinc sulfide core/shells via a thiol at the end of a linker arm. This conjugate has applications in biological assays and biological imaging.

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