Fontan Liver Lesions: Not Always HCC

Christiane Haeffele, MD, MPH; Avin Aggarwal, MBBS; Glen Lutchman, MD; Gruschen R. Veldtman, MD; Fred M. Wu, MD; George K. Lui, MD

JACC: Case Reports (Aug 2019)

Fontan Liver Lesions: Not Always HCC

Christiane Haeffele, MD, MPH,
Avin Aggarwal, MBBS,
Glen Lutchman, MD,
Gruschen R. Veldtman, MD,
Fred M. Wu, MD,
George K. Lui, MD

Affiliations

Christiane Haeffele, MD, MPH: Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Palo Alto, California; Department of Pediatrics, Division of Pediatric Cardiology, Stanford University, Palo Alto, California; Address for correspondence: Dr. Christiane Haeffele, Stanford University, 870 Quarry Road Extension, Palo Alto, California 94304.
Avin Aggarwal, MBBS: Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, California
Glen Lutchman, MD: Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, California
Gruschen R. Veldtman, MD: Cincinnati Children’s Hospital Adolescent and Adult Congenital Heart Program, Cincinnati, Ohio
Fred M. Wu, MD: Department of Cardiology, Boston Children’s Hospital, Boston, Massachusetts; Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
George K. Lui, MD: Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Palo Alto, California; Department of Pediatrics, Division of Pediatric Cardiology, Stanford University, Palo Alto, California

Journal volume & issue: Vol. 1, no. 2
pp. 175 – 178

Abstract

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A 24-year-old Fontan procedure patient underwent surveillance liver cardiac magnetic resonance imaging. Findings were suggestive of hepatocellular carcinoma (HCC). Currently, HCC is diagnosed based on imaging alone. Given her otherwise reassuring clinical profile, she underwent liver biopsy. Pathology demonstrated focal nodular hyperplasia. This raises concern for overdiagnosis of HCC in Fontan patients without tissue confirmation. (Level of Difficulty: Advanced.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

About the journal

Abstract

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