Emerging Infectious Diseases (Dec 2009)

Dobrava-Belgrade Virus Spillover Infections, Germany

  • Mathias Schlegel,
  • Boris Klempa,
  • Brita Auste,
  • Margrit Bemmann,
  • Jonas Schmidt-Chanasit,
  • Thomas Büchner,
  • Martin H. Groschup,
  • Markus Meier,
  • Anne Balkema-Buschmann,
  • Hinrich Zoller,
  • Detlev H. Krüger,
  • Rainer G. Ulrich

DOI
https://doi.org/10.3201/eid1512.090923
Journal volume & issue
Vol. 15, no. 12
pp. 2017 – 2020

Abstract

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We present the molecular identification of Apodemus agrarius (striped field mouse) as reservoir host of the Dobrava-Belgrade virus (DOBV) lineage DOBV-Aa in 3 federal states of Germany. Phylogenetic analyses provided evidence for multiple spillover of DOBV-Aa to A. flavicollis, a crucial prerequisite for host switch and genetic reassortment.

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