Clinical Case Reports (Jan 2021)

An unusual and severe case of paclitaxel‐induced hand‐foot syndrome

  • Ichrak Ben Abdallah,
  • Sonia Ben Nasr,
  • Aref Zribi,
  • Jihene Ayarai,
  • Sana Fendri,
  • Balti Mehdi,
  • Haddaoui Abderrazek

DOI
https://doi.org/10.1002/ccr3.3573
Journal volume & issue
Vol. 9, no. 1
pp. 594 – 596

Abstract

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Abstract Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechallenge, to prevent such severe HFS requiring long‐time recovery.

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