KI-H2O2 promoted intramolecular oxidative CH Functionalization: Synthesis of Benzo[d]thiazol-2-amines

Abstract

This work reported a novel, efficient and green technique for the synthesis of N-substituted benzothiazoles using KI/H2O2 in DCM via intramolecular oxidative CH functionalization was carried out. The simple isolation, mild reaction conditions, easy purification without column with good yields, rendering the methodology accessible herein highly eco-friendly compare to existing method.

Keywords

• Thiocarbamides
• KI/H2O2
• DCM
• Oxidative Cyclization
• C–S coupling product