An Open-Source Wireless Electrophysiological Complex for In Vivo Recording Neuronal Activity in the Rodent’s Brain
Alexander Erofeev,
Dmitriy Kazakov,
Nikita Makarevich,
Anastasia Bolshakova,
Evgenii Gerasimov,
Arseniy Nekrasov,
Alexey Kazakin,
Ivan Komarevtsev,
Marina Bolsunovskaja,
Ilya Bezprozvanny,
Olga Vlasova
Affiliations
Alexander Erofeev
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Dmitriy Kazakov
National Technology Initiative Center for Advanced Manufacturing Technologies, Laboratory of Industrial Data Streaming Systems, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Nikita Makarevich
National Technology Initiative Center for Advanced Manufacturing Technologies, Laboratory of Industrial Data Streaming Systems, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Anastasia Bolshakova
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Evgenii Gerasimov
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Arseniy Nekrasov
Neuropribor, Limited Liability Company, 194223 Saint Petersburg, Russia
Alexey Kazakin
Laboratory of Nano- and Microsystem Technology, Joint Institute of Science and Technology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Ivan Komarevtsev
Laboratory of Nano- and Microsystem Technology, Joint Institute of Science and Technology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Marina Bolsunovskaja
National Technology Initiative Center for Advanced Manufacturing Technologies, Laboratory of Industrial Data Streaming Systems, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Ilya Bezprozvanny
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Olga Vlasova
Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia
Multi-electrode arrays (MEAs) are a widely used tool for recording neuronal activity both in vitro/ex vivo and in vivo experiments. In the last decade, researchers have increasingly used MEAs on rodents in vivo. To increase the availability and usability of MEAs, we have created an open-source wireless electrophysiological complex. The complex is scalable, recording the activity of neurons in the brain of rodents during their behavior. Schematic diagrams and a list of necessary components for the fabrication of a wireless electrophysiological complex, consisting of a base charging station and wireless wearable modules, are presented.
