Журнал инфектологии (Oct 2020)

Characteristics of measles immunity in students of the pediatric faculty of a medical university

  • D. O. Ivanov,
  • V. N. Timchenko,
  • E. B. Pavlova,
  • E. V. Barakina,
  • T. M. Chernova,
  • N. V. Pavlova,
  • O. V. Bulina,
  • A. N. Nazarova

DOI
https://doi.org/10.22625/2072-6732-2020-12-4-58-64
Journal volume & issue
Vol. 12, no. 4
pp. 58 – 64

Abstract

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Objective: to evaluate the intensity of measles immunity in students of I–VI courses of the pediatric faculty of St. Petersburg State Medical University.Materials and methods: titers of antibodies to measles virus were determined in 986 students of I–VI courses in May –June 2019. The level of measles antibodies was determined by enzyme-linked immunosorbent assay.Results: positive (protective) titres of measles antibodies were detected in 555 people. (56.4%), the absence of measles immunity was found in 431 people. (43.6%), including 57 people. (5.8%) specific antibodies were not detected. The relationship between the level of collective immunity and the duration of the period after the last vaccination against measles was revealed.Conclusions: in the majority of examined students (96.2%), protective titers of measles antibodies remained for 10 years after the last vaccination. Subsequently, a significant decrease in the level of measles antibodies was noted. All students who do not have a protective IgG titer are shown measles vaccination with live measles vaccine in accordance with the instructions for use.

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