Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study

Antonio Metastasio; Antonio Metastasio; Elisabeth Prevete; Darshan Singh; Oliver Grundmann; Walter C. Prozialeck; Charles Veltri; Giuseppe Bersani; Ornella Corazza; Ornella Corazza

doi:10.3389/fpsyt.2020.594816

Frontiers in Psychiatry (Nov 2020)

Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study

Antonio Metastasio,
Antonio Metastasio,
Elisabeth Prevete,
Darshan Singh,
Oliver Grundmann,
Walter C. Prozialeck,
Charles Veltri,
Giuseppe Bersani,
Ornella Corazza,
Ornella Corazza

Affiliations

Antonio Metastasio: School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom
Antonio Metastasio: NHS Camden and Islington Trust, London, United Kingdom
Elisabeth Prevete: Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Darshan Singh: Centre for Drug Research, Universiti Sains Malaysia, Minden, Malaysia
Oliver Grundmann: Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States
Walter C. Prozialeck: Department of Pharmacology, Midwestern University, Downers Grove, IL, United States
Charles Veltri: Department of Pharmaceutical Sciences, Midwestern University, Glendale, AZ, United States
Giuseppe Bersani: Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Ornella Corazza: School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom
Ornella Corazza: Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy

DOI: https://doi.org/10.3389/fpsyt.2020.594816
Journal volume & issue: Vol. 11

Abstract

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Among the symptoms of COVID-19 fever, general malaise, pain and aches, myalgia, fatigue, and headache can affect the quality of life of patients, even after the end of the acute phase of the infection and can be long lasting. The current treatment of these symptoms, also because COVID-19 patients have been asked not to use non-steroidal anti-inflammatory drugs (NSAIDs), in particular ibuprofen are often unsatisfactory. Among the above mentioned symptoms malaise and fatigue seem the most difficult to treat. In this case report we describe the use of kratom (Mitragyna speciosa) by a patient with confirmed COVID-19 infection. What we observed was a fast and sustained relieve of the above mentioned symptoms.

Published in Frontiers in Psychiatry

ISSN: 1664-0640 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry
Website: https://www.frontiersin.org/journals/psychiatry

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