P717: AG946, A PYRUVATE KINASE (PK) ACTIVATOR IMPROVES PK PROPERTIES AND RED BLOOD CELL (RBC) METABOLISM UPON EX VIVO TREATMENT OF RBCS FROM PATIENTS WITH MYELODYSPLASTIC SYNDROMES

• Jonathan de Wilde,
• Titine Ruiter,
• Brigitte van Oirschot,
• Judith Jans,
• Lenny Dang,
• Megan Wind-Rotolo,
• Wouter van Solinge,
• Anna van Rhenen,
• Richard Van Wijk,
• Minke Rab

Affiliations

Jonathan de Wilde

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands

Titine Ruiter

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands

Brigitte van Oirschot

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands

Judith Jans

2 University Medical Center Utrecht, Utrecht University, Section Metabolic Diagnostics, Department of Genetics, Utrecht, The Netherlands

Lenny Dang

3 Agios Pharmaceuticals, Inc., Cambridge, MA, United States

Megan Wind-Rotolo

3 Agios Pharmaceuticals, Inc., Cambridge, MA, United States

Wouter van Solinge

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands

Anna van Rhenen

4 University Medical Center Utrecht, Utrecht University, Department of Hematology, Utrecht, The Netherlands

Richard Van Wijk

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands

Minke Rab

1 University Medical Center Utrecht, Utrecht University, Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, Utrecht, The Netherlands