Successful use of acitretin in an indian child with lipoid proteinosis

Abstract

Introduction: Lipoid proteinosis is a rare autosomal recessive disease, characterized by deposition of Periodic Acid‒Schiff-positive hyaline material in the skin, mucous membrane of the upper aerodigestive tract, and different organs of the body, resulting in varied clinical manifestations. Case Report: We report a case of lipoid proteinosis in a 7-year-old boy who responded well to oral acitretin therapy. Discussion: Lipoid proteinosis is a rare disease entity, and very few reports have been mentioned in the literature based on its treatment modalities, with each treatment showing varied success rates. Oral acitretin can prove useful in cases of failure or inadequate response to other treatment, as seen in our case.

Keywords

• acitretin
• ecm1
• hyaline material
• lipoid proteinosis
• moniliform blepharosis