An outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021

Juan Li; Nan Ni; Yanan Cui; Shuai Zong; Xue Yao; Tao Hu; Mengyuan Cao; Yong Zhang; Peiqiang Hou; Michael J. Carr; Weijia Xing; Hong Zhou; Weifeng Shi

doi:10.1080/22221751.2022.2114855

Emerging Microbes and Infections (Dec 2022)

An outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021

Juan Li,
Nan Ni,
Yanan Cui,
Shuai Zong,
Xue Yao,
Tao Hu,
Mengyuan Cao,
Yong Zhang,
Peiqiang Hou,
Michael J. Carr,
Weijia Xing,
Hong Zhou,
Weifeng Shi

Affiliations

Juan Li: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Nan Ni: Taian Center for Disease Control and Prevention, Taian, People’s Republic of China
Yanan Cui: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Shuai Zong: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Xue Yao: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Tao Hu: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Mengyuan Cao: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Yong Zhang: Taishan District Center for Disease Control and Prevention, Taian, People’s Republic of China
Peiqiang Hou: Taian Center for Disease Control and Prevention, Taian, People’s Republic of China
Michael J. Carr: National Virus Reference Laboratory, School of Medicine, University College Dublin, Dublin, Ireland
Weijia Xing: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Hong Zhou: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China
Weifeng Shi: Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, People’s Republic of China

DOI: https://doi.org/10.1080/22221751.2022.2114855
Journal volume & issue: Vol. 11, no. 1
pp. 2207 – 2210

Abstract

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In 2021, twenty children exhibiting influenza-like illnesses were reported from a kindergarten in Shandong Province, China. Eleven genomes of Coxsackievirus A4 (CV-A4) were obtained from the pediatric cases, sharing <93% genome sequence identities with known CV-A4 strains. Further analyses suggested potential genetic recombination in the P3 region of the novel strains.

Published in Emerging Microbes and Infections

ISSN: 2222-1751 (Online)
Publisher: Taylor & Francis Group
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Science: Microbiology
Website: https://www.tandfonline.com/journals/temi

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