Communications Chemistry (May 2021)
Functionalized Au15 nanoclusters as luminescent probes for protein carbonylation detection
- Guillaume F. Combes,
- Hussein Fakhouri,
- Christophe Moulin,
- Marion Girod,
- Franck Bertorelle,
- Srestha Basu,
- Romain Ladouce,
- Martina Perić Bakulić,
- Željka Sanader Maršić,
- Isabelle Russier-Antoine,
- Pierre-François Brevet,
- Philippe Dugourd,
- Anita Krisko,
- Katarina Trajković,
- Miroslav Radman,
- Vlasta Bonačić-Koutecký,
- Rodolphe Antoine
Affiliations
- Guillaume F. Combes
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Hussein Fakhouri
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Christophe Moulin
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Marion Girod
- Univ Lyon, CNRS, Université Claude Bernard Lyon 1, Institut des Sciences Analytiques, UMR 5280, 5 rue de la Doua
- Franck Bertorelle
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Srestha Basu
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Romain Ladouce
- Mediterranean Institute for Life Sciences (MedILS)
- Martina Perić Bakulić
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Željka Sanader Maršić
- Faculty of Science, University of Split
- Isabelle Russier-Antoine
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Pierre-François Brevet
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Philippe Dugourd
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- Anita Krisko
- Department of Experimental Neurodegeneration, University Medical Center Goettingen
- Katarina Trajković
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Miroslav Radman
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Vlasta Bonačić-Koutecký
- Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM), Faculty of Science, University of Split
- Rodolphe Antoine
- Univ Lyon, Univ Claude Bernard Lyon 1, CNRS, Institut Lumière Matière
- DOI
- https://doi.org/10.1038/s42004-021-00497-z
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 11
Abstract
Atomically precise gold nanoclusters hold promise as non-linear optical probes for biological imaging. Here functionalized luminescent gold nanoclusters bind free carbonyls via oxime bond formation, allowing detection of carbonylated proteins via gel electrophoresis and fluorescence imaging.
