PLoS ONE (Jan 2015)

Babesiosis Occurrence among the Elderly in the United States, as Recorded in Large Medicare Databases during 2006-2013.

  • Mikhail Menis,
  • Richard A Forshee,
  • Sanjai Kumar,
  • Stephen McKean,
  • Rob Warnock,
  • Hector S Izurieta,
  • Rahul Gondalia,
  • Chris Johnson,
  • Paul D Mintz,
  • Mark O Walderhaug,
  • Christopher M Worrall,
  • Jeffrey A Kelman,
  • Steven A Anderson

DOI
https://doi.org/10.1371/journal.pone.0140332
Journal volume & issue
Vol. 10, no. 10
p. e0140332

Abstract

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BackgroundHuman babesiosis, caused by intraerythrocytic protozoan parasites, can be an asymptomatic or mild-to-severe disease that may be fatal. The study objective was to assess babesiosis occurrence among the U.S. elderly Medicare beneficiaries, ages 65 and older, during 2006-2013.MethodsOur retrospective claims-based study utilized large Medicare administrative databases. Babesiosis occurrence was ascertained by recorded ICD-9-CM diagnosis code. The study assessed babesiosis occurrence rates (per 100,000 elderly Medicare beneficiaries) overall and by year, age, gender, race, state of residence, and diagnosis months.ResultsA total of 10,305 elderly Medicare beneficiaries had a recorded babesiosis diagnosis during the eight-year study period, for an overall rate of about 5 per 100,000 persons. Study results showed a significant increase in babesiosis occurrence over time (pConclusionOur study reveals increasing babesiosis occurrence among the U.S. elderly during 2006-2013, with highest rates in the babesiosis-endemic states. The study also shows variation in babesiosis occurrence by age, gender, race, state of residence, and diagnosis months. Overall, our study highlights the importance of large administrative databases in assessing the occurrence of emerging infections in the United States.