Nature Communications (Mar 2023)

Distinct roles of Arabidopsis ORC1 proteins in DNA replication and heterochromatic H3K27me1 deposition

  • Zaida Vergara,
  • María S. Gomez,
  • Bénédicte Desvoyes,
  • Joana Sequeira-Mendes,
  • Kinda Masoud,
  • Celina Costas,
  • Sandra Noir,
  • Elena Caro,
  • Victoria Mora-Gil,
  • Pascal Genschik,
  • Crisanto Gutierrez

DOI
https://doi.org/10.1038/s41467-023-37024-8
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 13

Abstract

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The dynamics of DNA replication factors is crucial for cell cycle progression. Arabidopsis encode two origin recognition complex 1 proteins, ORC1a and ORC1b, with distinct roles in DNA replication and deposition of heterochromatic H3K27me1, respectively.