PLoS Biology (Oct 2023)

A call to implement preclinical study registration in animal ethics review.

  • Matthew S Jeffers,
  • Aileen MacLellan,
  • Marc T Avey,
  • Julia Ml Menon,
  • Janet Sunohara-Neilson,
  • Dean A Fergusson,
  • Manoj M Lalu

DOI
https://doi.org/10.1371/journal.pbio.3002293
Journal volume & issue
Vol. 21, no. 10
p. e3002293

Abstract

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Protocol registration is required in clinical trials. Registration of animal studies could improve research transparency and reduce redundancy, yet uptake has been minimal. Integrating study registration into institutional approval of animal use protocols is a promising approach to increase uptake.