Role of diffusion weighted imaging and proton magnetic resonance spectroscopy in ring enhancing brain lesions

Abstract

Aim of the work: To assess and compare the usefulness and efficacy of both diffusion weighted imaging (DWI) and proton magnetic resonance spectroscopy (1HMRS) in brain lesions with ring enhancement in post contrast T1WI and to determine which method is more effective. Subjects and methods: Thirty patients with ring-enhanced brain lesions were classified into 2 groups, abscess group (11 patients) and tumor group (19 patients), were examined using diffusion-weighted imaging (DWI) and H-proton magnetic resonance spectroscopy (1HMRS). Results: Restricted diffusion and low ADC value were seen in 9 (81%) patients of brain abscesses, however, free diffusion and high ADC value were found in 18 (94%) patients with necrotic brain tumor. The abscess group showed aminoacids, acetate and lactate in 9 patients and extra peak of succinate was found in 1 patient; however in the tumor group lactate alone was found in 12 patients, lactate and choline were seen in 5 patients, none of the patients showed amino acids, succinate or acetate. Conclusion: Both DWI and 1HMRS are useful and efficient imaging techniques in ring enhancing brain lesions and differentiate between pyogenic brain abscesses and necrotic tumors, but DWI is accurate, has less imaging time than 1HMRS, also is available in many imaging centers.

Keywords

• Ring enhancing
• Brian abscess
• Necrotic brain tumors
• Diffusion-weighted image
• MR spectroscopy