INDIVIDUALIZATION OF CANCER TREATMENT: CONTRIBUTION OF OMICS TECHNOLOGIES TO CANCER DIAGNOSTIC

Abstract

Cancer is a disease, which explicitly illustrates success, failures and challenges of the modern biomedical research. Technology development has been the driving force of improvements in the cancer treatment. Introduction into clinical practice of genomics, RNA profiling and proteomics technologies have provided a basis for development of novel diagnostic, drugs and treatments. In this chapter, contributions of OMICs technologies to personalization of cancer diagnostic and treatment are discussed. The focus is on technologies that showed capacity to deliver diagnostic that may be used in the clinic as routine tests. Three clinical cases are presented to illustrate already available individualized cancer diagnostic.

Keywords

• personalized cancer medicine
• genomics
• transcriptomics
• proteomics
• metabolomics
• diagnostic