Respiratory Syncytial Virus Vaccine Induced Thrombotic Microangiopathy

Abstract

Robert Seby,1 Benjamin J McCormick,1 Emily Wolf,2 Justin Kuhlman,2 Nikita Jhawar,1 Sven Peter Oman,1 Adam M Kase,2 Chancey Christenson,3 Marwan Shaikh2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Department of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Pathology and Transfusion Medicine, Mayo Clinic, Jacksonville, FL, USACorrespondence: Robert Seby, Email [email protected]: Microangiopathic hemolytic anemia with associated multiorgan failure is a medical emergency. The differential diagnosis for microangiopathic hemolytic anemia is broad and requires a systematic, focused approach at ruling out serious causes. However, with the rise of new vaccines and sporadic reports of vaccine-induced microangiopathic hemolytic anemia, it is essential for providers to include vaccines as a potential cause on their differential diagnosis. Here, we report the first case of respiratory syncytial virus vaccine-induced microangiopathic hemolytic anemia, anuric renal failure, and metabolic encephalopathy in the world.Keywords: microangiopathic hemolytic anemia, respiratory syncytial virus, renal failure, metabolic encephalopathy

Keywords

• microangiopathic hemolytic anemia
• respiratory syncytial virus
• renal failure
• metabolic encephalopathy.