Pressurized intraperitoneal aerosol chemotherapy, reasons for interrupting treatment: a systematic review of the literature

Abstract

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) gives encouraging results in the treatment of peritoneal metastasis (PM). The current recommendations require at least 3 sessions of PIPAC. However, some patients do not complete the full treatment course and stop after only 1 or 2 procedures, hence the limited benefit. A literature review was performed, with search terms including “PIPAC” and “pressurised intraperitoneal aerosol chemotherapy.”

Keywords

• colon cancer
• gastric cancer
• mesothelioma
• peritoneal metastasis
• pipac
• pressurized intraperitoneal aerosol chemotherapy
• safety process