Review of in-vivo characterisation of corneal biomechanics

Bernardo T. Lopes; FangJun Bao; JunJie Wang; XiaoYu Liu; LiZhen Wang; Ahmed Abass; Ashkan Eliasy; Ahmed Elsheikh

Medicine in Novel Technology and Devices (Sep 2021)

Review of in-vivo characterisation of corneal biomechanics

Bernardo T. Lopes,
FangJun Bao,
JunJie Wang,
XiaoYu Liu,
LiZhen Wang,
Ahmed Abass,
Ashkan Eliasy,
Ahmed Elsheikh

Affiliations

Bernardo T. Lopes: School of Engineering, University of Liverpool, Liverpool, UK; Department of Ophthalmology, Federal Univerisity of Sao Paulo (UNIFESP), Sao Paulo, Brazil; Corresponding author. School of Engineering, University of Liverpool, Liverpool, L69 3GH, UK.
FangJun Bao: Eye Hospital, Wenzhou Medical University, Wenzhou, China; The Institution of Ocular Biomechanics, Wenzhou Medical University, Wenzhou, China; Corresponding author. Eye Hospital, Wenzhou Medical University, WenZhou City, ZheJiang Prov, 325027, China.
JunJie Wang: Eye Hospital, Wenzhou Medical University, Wenzhou, China; The Institution of Ocular Biomechanics, Wenzhou Medical University, Wenzhou, China
XiaoYu Liu: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China
LiZhen Wang: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China
Ahmed Abass: School of Engineering, University of Liverpool, Liverpool, UK
Ashkan Eliasy: School of Engineering, University of Liverpool, Liverpool, UK
Ahmed Elsheikh: School of Engineering, University of Liverpool, Liverpool, UK; Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK

Journal volume & issue: Vol. 11
p. 100073

Abstract

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The study of corneal biomechanics in vivo has been evolving fast in recent years. While an organised corneal structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This review focuses on three techniques that are available for clinical use, namely the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA), the Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) and the Brillouin Optical Scattering System (Intelon Optics Inc., Lexington, MA, USA). The principles and the main parameters of each device are discussed along with their strategies to improve accuracy in the IOP measurement, corneal ectasia diagnosis, evaluation of corneal cross-linking procedures, and planning of corneal refractive surgeries.

Published in Medicine in Novel Technology and Devices

ISSN: 2590-0935 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General): Medical technology
Website: https://www.journals.elsevier.com/medicine-in-novel-technology-and-devices

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