Сахарный диабет (Mar 2010)
The role of apoptosis in pathogenesis of type 1 diabetes mellitus
Abstract
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.
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