The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

Abstract

The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.

Keywords

• α-Haloketones
• annelated heterocycles
• oxygen nucleophiles
• nitrogen nucleophiles
• sulfur nucleophiles
• carbon nucleophiles