Emerging Infectious Diseases (Jul 2021)

Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020

  • Teena Mohan,
  • Ha T. Nguyen,
  • Krista Kniss,
  • Vasiliy P. Mishin,
  • Angiezel A. Merced-Morales,
  • Jennifer Laplante,
  • Kirsten St. George,
  • Patricia Blevins,
  • Anton Chesnokov,
  • Juan A. De La Cruz,
  • Rebecca Kondor,
  • David E. Wentworth,
  • Larisa V. Gubareva

DOI
https://doi.org/10.3201/eid2707.204593
Journal volume & issue
Vol. 27, no. 7
pp. 1953 – 1957

Abstract

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Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.

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