Low FDG uptake in lung metastasis despite high FDG uptake in a primary adenoid cystic carcinoma of a sublingual gland

Kenichiro Otsuka, MD; Makoto Otsuka, MD; Takayuki Matsunaga, MD; Takashi Hirano, MD; Miyuki Abe, MD; Atsushi Osoegawa, MD; Kenji Sugio, MD; Tsutomu Daa, MD; Yoshiki Asayama, MD

Radiology Case Reports (Aug 2024)

Low FDG uptake in lung metastasis despite high FDG uptake in a primary adenoid cystic carcinoma of a sublingual gland

Kenichiro Otsuka, MD,
Makoto Otsuka, MD,
Takayuki Matsunaga, MD,
Takashi Hirano, MD,
Miyuki Abe, MD,
Atsushi Osoegawa, MD,
Kenji Sugio, MD,
Tsutomu Daa, MD,
Yoshiki Asayama, MD

Affiliations

Kenichiro Otsuka, MD: Department of Radiology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan; Corresponding author.
Makoto Otsuka, MD: Department of Radiation Oncology, Oita Koseiren Tsurumi Hospital, 4333 Tsurumi, Beppu, Oita 874-8585, Japan
Takayuki Matsunaga, MD: Department of Otolaryngology-Head and Neck Surgery, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Takashi Hirano, MD: Department of Otolaryngology-Head and Neck Surgery, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Miyuki Abe, MD: Department of Thoracic and Breast Surgery, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Atsushi Osoegawa, MD: Department of Thoracic and Breast Surgery, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Kenji Sugio, MD: Department of Thoracic and Breast Surgery, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Tsutomu Daa, MD: Department of Diagnostic Pathology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan
Yoshiki Asayama, MD: Department of Radiology, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama, Yufu, Oita 879-5593, Japan

Journal volume & issue: Vol. 19, no. 8
pp. 3195 – 3199

Abstract

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Adenoid cystic carcinoma is a rare malignant tumor that primarily occurs in the salivary glands. There are few reports of sublingual gland adenoid cystic carcinoma with lung metastases on which 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was performed. We report the case of a 57-year-old Japanese woman with an adenoid cystic carcinoma of the sublingual gland with lung metastases in whom the FDG uptake of the lung metastasis was low despite high FDG uptake in the primary lesion. The pathological examination revealed that solid components were more visible and the Ki-67 index was more positive in the primary lesion compared to the metastatic lesion. We speculate that differences in tumor growth ability might have resulted in the differences in FDG uptake. This case demonstrates that significant differences might occur in the FDG uptake between primary and metastatic tumors.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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