A New Neolignan Glycoside from the Leaves of Acer truncatum

Abstract

A new neolignan glycoside, (7R,8R)-7,8-dihydro-9′-hydroxyl-3′-methoxyl- 8-hydroxymethyl-7-(4-hydroxy-3-methoxyphenyl)-1′-benzofuranpropanol 9′-O-β-D- glucopyranoside (1) was isolated from the leaves of Acer truncatum along with (7R,8R)-7,8-dihydro-9′-hydroxyl-3′-methoxyl-8-hydroxymethyl-7-(4-O-α-L-rhamno- pyranosyloxy-3-methoxyphenyl)-1′-benzofuranpropanol (2), schizandriside (3), lyoniresinol (4), berchemol (5), (-)-pinoresinol-4-O-β-D-glucopyranoside (6), hecogenin (7), chlorogenic acid (8) and neochlorogenic acid (9). Their structures were elucidated on the basis of extensive spectroscopic data. The absolute configuration of compounds 1 was established by its CD spectrum. The antibacterial activities of compounds 1-7 were evaluated.

Keywords

• Acer truncatum
• Aceraceae
• neolignan glycosides
• antibacterial activity