Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

• Antonia Carla Testa,
• Sabine Tejpar,
• Ignace Vergote,
• Valentina Chiappa,
• An Coosemans,
• Thaïs Baert,
• Chiara Landolfo,
• Wouter Froyman,
• Dirk Timmerman,
• Tom Bourne,
• Abhishek D Garg,
• Patrizia Agostinis,
• Louis Boon,
• Daniela Fischerova,
• Caroline Van Holsbeke,
• Jenny Sprooten,
• Ann Vankerckhoven,
• Isaure Vanmeerbeek,
• Daniel M Borras,
• Yani Berckmans,
• Roxanne Wouters,
• Raquel S Laureano,
• Dominique Schols

Affiliations

Antonia Carla Testa

Dipartimento Scienze della Salute della Donna e del Bambino, Fondazione Policlinico Universitario A. Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy

Sabine Tejpar

Laboratory for Molecular Digestive Oncology, Department of Oncology, KU Leuven, Leuven, Belgium

Ignace Vergote

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Valentina Chiappa

National Cancer Institute of Milan, Milan, Italy

An Coosemans

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Thaïs Baert

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Chiara Landolfo

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Wouter Froyman

Department of Development and Regeneration, KU Leuven, Leuven, Belgium

Dirk Timmerman

Department of Development and Regeneration, KU Leuven, Leuven, Belgium

Tom Bourne

Queen Charlotte`s and Chelsea Hospital, Imperial College, London, UK

Abhishek D Garg

Laboratory of Cell Stress & Immunity, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium

Patrizia Agostinis

Department of Cellular and Molecular Medicine, Cell Death Research and Therapy Laboratory, KU Leuven, Belgium

Louis Boon

JJP Biologics, Warsaw, Poland

Daniela Fischerova

Charles University, Praha, Czech Republic

Caroline Van Holsbeke

Ziekenhuis Oost-Limburg, Genk, Belgium

Jenny Sprooten

Laboratory of Cell Stress & Immunity, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium

Ann Vankerckhoven

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Isaure Vanmeerbeek

Laboratory of Cell Stress & Immunity, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium

Daniel M Borras

Laboratory of Cell Stress & Immunity, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium

Yani Berckmans

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Roxanne Wouters

Department of Oncology, Leuven Cancer Institute, Laboratory of Tumor Immunology and Immunotherapy, KU Leuven, Leuven, Belgium

Raquel S Laureano

Laboratory of Cell Stress & Immunity, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium

Dominique Schols

Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, KU Leuven, Leuven, Belgium